Friday, November 30, 2012

Video: Battle of the sexes, airport edition



>> reporter: kind of a bat of the sexes going on in the air these days.

>> the " wall street journal " points out in its airline travel blog there are five or six core differences. we'll put some of them up. women shrink and curl up in their seat to avoid contact with strangers.

>> true.

>> men spread out and take up the leg room and the arm rest, and women get cold and want blankets while men like it cold.

>> we do.

>> i like the overhead space. i want to get on early, put that overhead space because i don't want to check.

>> that's a big difference.

>> checking or carrying on.

>> any strategies?

>> i exploit my children, use the small child. they are under three feet, the little one is.

>> her children are 20 years old. very odd.

>> i think there's something to trying to get in there before and then you have to stand in the back of the line and wait for everybody to put their luggage up.

Source: http://video.today.msnbc.msn.com/today/50024103/

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Video: Biden fills shopping cart at new Costco



>>> and while those two had lunch, he went to costco, where he proudly pointed out he is a gold member. he toured the very first one in the district of columbia , filled the cart with supplies, a flat screen tv. somehow, though, he passed up the chicken.

>>> and speaking of optics, this was all optics, and joe biden talked politics, and the

Source: http://video.msnbc.msn.com/nightly-news/50018472/

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Charlie Sheen Invites Angus T. Jones on His Show

You knew it wouldn't be long before Charlie Sheen waded into the troubled waters at Two and a Half Men this week. And for once, he got to sit back and commentate while someone else -- Angus T. Jones -- flailed in the deep end.

Source: http://www.ivillage.com/charlie-sheen-invites-angus-t-jones-his-show/1-a-505336?dst=iv%3AiVillage%3Acharlie-sheen-invites-angus-t-jones-his-show-505336

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Thursday, November 29, 2012

Only A Limited Time Offer!Special Windows 8 Package!

As we have celebrated on October 26, Windows 8 has been out for almost a week, and we got something special in store for all you ?moe? fans out there!

Many of you may know of this already, but in Japan, mainly Akihabara in Tokyo and Nipponbashi in Osaka have a limited special package for the Windows 8 Pro.

These special packages feature 2 new mascots that Microsoft Japan had created specifically for Windows 8, Madobe Yuu and Madobe Ai, which are homophones for the English words ?You? and ?I?. It includes not only the new OS, but also a theme wallpaper, the characters? voices, and a Microsoft wedge mouse that will display the Windows 8 logo along with the respective character package. So if anyone of you out there have become infatuated with either Yuu or Ai, don?t wait! (Please note that this is the DSP edition of Windows 8 Pro.)

Here at GeekStuff4U, we were able to get our hands on only a few copies of the Akihabara versions, both Yuu and Ai versions. The price of the software will be 28,455 JPY (to estimate the price in your own currency, please utilize Google, as it is everyone?s friend!) So if there are any of you who are interested in this product, please let us know at our contact form by Sunday night, November 4th, so that finalization of the order will be made on Monday, Japan time. Remember, ONLY A FEW LEFT SO SPAM US ASAP!

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Source: http://blog.geekstuff4u.com/only-a-limited-time-offerspecial-windows-8-package/

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The Story Of Adku, And Why Andrew Mason Isn?t The Problem At Groupon

FallguytitlescreenIn February of this year, Groupon acquired Adku, an e-commerce data targeting startup staffed with a whip-smart team that included several relatively prominent ex-Googlers. It was one of a series of acqui-hire deals Groupon executed as part of its strategy to staff up its Silicon Valley office with the best engineers money can buy.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/MwXTjmLkREc/

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Wednesday, November 28, 2012

Parenting4Tomorrow: Baby Boomer Family Life

The first of the baby boomers are getting a lot of press lately as they?turn 60.?Researchers have been exploring how this large generation impacts not only our political and cultural climate, but our families as well.

First, boomers have paved the way to more diverse family lives. They have "delayed marriage to a degree never recorded in the United States" and, as young adults, were more likely than any other generation to leave home and set up their own households before marriage. They are also more likely to "live together" outside of marriage. So many boomer couples have done this that we tend to forget how rare and frowned-upon this once was.

Second, boomers have looked for marriage based on a strong emotional bond and room for each person to develop as an individual. These demands on married life can make it unstable. Boomers' high rates of divorce and common remarriage have reinforced a family pattern of "serial monogamy."

Third, boomers have transformed family roles and relationships: "Boomer women have redefined the role of mother to 'working mother' by combining motherhood with work outside the home". Fathers have also become more involved in family life, spending more time with their children and in sharing the housework.

Because these arrangements and roles are new, boomers have had to develop their own ways of doing things and, some suggest, "have often been confused by their own lives". But boomers really are paving the way for new ways of family life in the larger U.S. society.

Suzanna Smith, associate professor, Department of Family, Youth and Community Sciences, Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida.

Source: http://parenting4tomorrow.blogspot.com/2012/11/baby-boomer-family-life.html

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UN agency: 2012 warmer than normal despite La Nina

DOHA, Qatar (AP) ? Despite early cooling from La Nina, 2012 is on track to become one of the top 10 hottest years on record, with the U.S. experiencing extreme warmth and Arctic Sea ice shrinking to its lowest extent, the U.N. weather agency said Wednesday.

In a statement released at international climate talks in Qatar, the World Meteorological Organization said the "alarming rate" of the Arctic melt highlights the far-reaching changes caused by global warming.

"Climate change is taking place before our eyes and will continue to do so as a result of the concentrations of greenhouse gases in the atmosphere, which have risen constantly and again reached new records," WMO Secretary-General Michel Jarraud said.

Delegates from nearly 200 countries are meeting in the Qatari capital of Doha to discuss ways of slowing climate change, including by cutting emissions of greenhouse gases that scientists say are warming the planet, melting ice caps, raising sea levels, and changing rainfall patterns with impacts on floods and droughts.

Discord between rich and poor countries on who should do what has kept the two-decade-old U.N. talks from delivering on that goal, and global emissions are still going up.

The WMO said global temperatures rose after initial cooling caused by the La Nina weather oscillation, with major heat waves in the U.S. and Europe. Average temperatures in January-October were the highest on record in the continental U.S., and the ninth highest worldwide.

Before that, a cold spell had much of the Eurasian continent in an icy grip between late January and mid-February, when temperatures in eastern Russia plunged to -50 degrees C (-58 F).

Cyclone activity was normal globally, but above average in the Atlantic, where 10 storms reached hurricane strength, including Sandy, which wreaked havoc across the Caribbean and the U.S. east coast.

Sandy wasn't the strongest cyclone, though. That was typhoon Sanba, which struck the Philippines, Japan, and the Korean Peninsula, "dumping torrential rain and triggering floods and landslides that affected thousands of people and caused millions in U.S. dollars in damage," the WMO said.

Droughts impacted the U.S., Russia, parts of China and northern Brazil. Nigeria saw exceptional floods, while southern China saw its heaviest rainfall in three decades.

But of all the weather events in 2012, the most ominous to climate scientists was the loss of ice cover on the North Pole. In September, scientists at the National Snow and Ice Data Center in Colorado said Arctic Sea ice measured 1.32 million square miles (3.41 million sq. kilometers) ? which is 18 percent less than the previous record low, set in 2007. Records go back to 1979 based on satellite tracking.

The scientists said their computer models predict the Arctic could become essentially free of ice in the summer by 2050, but added that current trends show ice melting faster than the computers are predicting.

___

Follow Karl Ritter on www.twitter.com/karl_ritter

Source: http://news.yahoo.com/un-agency-2012-warmer-normal-despite-la-nina-113850303.html

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ConAgra gobbles up store brands with Ralcorp deal

This March 21, 2011, file photo shows a sign for ConAgra Foods' world headquarters in Omaha, Neb. ConAgra Foods is buying private-label food producer Ralcorp for about $4.95 billion, which will make it the biggest private-label packaged food business in North America. ConAgra Foods Inc. said Tuesday, Nov. 27, 2012, that the deal is expected to close by March 31, 2013 and needs Ralcorp shareholder approval. (AP Photo/Nati Harnik, File)

This March 21, 2011, file photo shows a sign for ConAgra Foods' world headquarters in Omaha, Neb. ConAgra Foods is buying private-label food producer Ralcorp for about $4.95 billion, which will make it the biggest private-label packaged food business in North America. ConAgra Foods Inc. said Tuesday, Nov. 27, 2012, that the deal is expected to close by March 31, 2013 and needs Ralcorp shareholder approval. (AP Photo/Nati Harnik, File)

NEW YORK (AP) ? ConAgra Foods is set to become the nation's biggest maker of store-brand foods, with a $5 billion purchase of Ralcorp that expands its stake in the growing market for cereals, crackers and other packaged foods sold under private labels.

The deal announced Tuesday caps a year of acquisitions for ConAgra, which makes brands including Banquet, Chef Boyardee and Marie Callender's. The company, based in Omaha, Neb., also made multiple attempts to buy Ralcorp last year.

The latest bid for Ralcorp comes at a time when private-label brands ? also known as store brands or house brands ? are gaining popularity with price-conscious shoppers. Supermarkets and drug stores have also been working to improve the image of their brands as a way to control the rising costs for name brands.

In a conference call with analysts, ConAgra CEO Gary Rodkin noted that private-label products are growing at twice the rate of name brands and now account for 18 percent of the overall packaged food market.

In a new report this week, however, market researcher SymphonyIRI wrote that the growth of private label products has ebbed and "hit a proverbial glass ceiling." It also said that the private-label market has entered a phase of "pockets of growth" among categories, rather than a general expansion. Separately on Tuesday, Ralcorp attributed an 8 percent increase in net sales to acquisitions and higher prices, which offset lower volumes.

Like many other packaged food companies, ConAgra already made private-label products along with name-brand foods that include Slim Jim, Healthy Choice and Hebrew National. With the Ralcorp purchase, about a quarter of the combined company's $18 billion in sales will now come from private labels. Ralcorp, based in St. Louis, makes products for a wide range of companies including Wal-Mart Stores Inc., Kroger Co. and McDonald's Corp.

Rather than merely mimicking name brands, Rodkin said that retailers increasingly want to cultivate customer loyalty by offering unique products. He cited CostCo and Trader Joe's as companies that are significantly developing their store brands.

"The private-label industry for the most part has been more emulation oriented," Rodkin said in a conference call with analysts. He said ConAgra would use its experience with name brands to innovate private label products.

Kevin Hunt, CEO of Ralcorp, noted the private-label business is about $100 billion but that the industry is very fragmented, meaning there's "a lot of opportunity" for further consolidation.

The companies did not say whether there would be any layoffs for their 36,000 employees, adding that the deal was about "growth." They said operational decisions would be made during the integration process.

This isn't the first time ConAgra has tried to buy Ralcorp. Last year, Ralcorp spurned several bids by ConAgra, including an offer for $5.17 billion, or $94 per share. At the time, Ralcorp's board said its plan to spin off its Post cereal business and build its private-label business would provide the best value for shareholders. The latest $90 per share deal by ConAgra is close to what it offered before Ralcorp's split with Post.

ConAgra will pay Ralcorp Holdings Inc. stockholders $90 per share, a 28 percent premium to its Monday closing price of $70.23. St. Louis-based Ralcorp currently has about 55 million outstanding shares, according to FactSet.

The companies value the transaction at about $6.8 billion, when debt is included. ConAgra said it plans to finance the acquisition mostly with available cash, existing credit facilities and new borrowings. It expects about $225 million in cost savings on an annual basis by the fourth full fiscal year after the deal closes.

The deal, which was unanimously approved by both companies' boards, is expected to close by March 31. It still needs Ralcorp shareholder approval.

ConAgra said that the buyout should be of modest benefit to its fiscal 2013 financial results. The company still anticipates fiscal 2013 earnings in a range of $2.03 to $2.06 per share, excluding the Ralcorp deal.

Analysts predict earnings of $2.06 per share.

Also on Tuesday, Ralcorp reported that its loss narrowed to $44.2 million, or 80 cents per share, for the quarter ended Sept. 30. That compares with a loss of $424.1 million, or $7.54 per share, in the year-ago period. Revenue rose to $1.07 billion from $990.4 million, on the strength of acquisitions and higher prices.

Results for both quarters reflected hedging and impairment charges, as well as costs for restructuring and plant closures.

Ralcorp shares jumped $18.59, or 26.5 percent, to $88.82 in Tuesday afternoon trading. ConAgra gained $1.40, or 5 percent, to $29.69.

___

Follow Candice Choi at www.twitter.com/candicechoi

AP Business Writer Josh Funk contributed to this report from Omaha, Neb.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2012-11-27-ConAgra%20Foods-Ralcorp/id-92c0ebda3af7484883dc77bb8ee21147

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Coupon Clippin' Mommy: Something About Silver Family Tree ...


Product Description: "Family Tree" This charming, handcrafted pendant is hand stamped with a whimsical family heart tree and comes with your choice of birthstones on a standard? 18" sterling silver plated link chain.?? All of the jewelry is fabricated by hand in a studio located near the sunny beaches of Clearwater, Florida.

This new line is only available for a limited time so if you want one, grab it now!

Review: I love hand stamped jewelry!? I wear my Something About Silver hand stamped ring almost everyday.? It has the kids names on it so it reminds me of them and helps me to keep them close in my thoughts.? The "Family Tree" necklace is a great way to bring the whole family together.? This is the only hand stamped item I have that includes myself and my husband.? The family tree you create doesn't have to be your immediate family.? Maybe you want to order one for Grandma or Great Grandma.? With the ability to add charms in the future this would make a great gift for a daughter or daughter in law on her wedding day.?
The chain is the perfect length for showcasing the family tree.? When I'm wearing the necklace the birthstones do move around a little bit.? For the most part they lay nicely on top of the tree.? While I don't plan on adding any birthstones anytime soon I like that you have the flexibility to add more at a future time.

Something About Silver has given me yet another great personalized jewelry piece that I can wear proudly and showcase some of the most important people in my life.? No matter who is on your holiday list you will be able to find something for them.? There is even a section with a few gifts for men in your life.? Holiday ornaments make a great hostess gift or special something for newlyweds and baby's first Christmas.? If you don't have time to wait for an item to be personalized there are some ready to ship items.? Head on over to Something About Silver and do some holiday shopping or pick something up for yourself!

Buy it: You can purchase rings, necklaces and other awesome personalized silver pieces at Something About Silver.? Use the code CCM10 to receive 10% off your order (exp. 12/14).

Win it: 1 lucky Coupon Clippin' Mommy reader will win a $40 Something About Silver gift certificate.

Mandatory Entry: Visit Something About Silver and let me know what your favorite item is.
Please make sure if your email address is not visible in your blogger profile you leave one in your initial entry!

Additional Entries:

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#win a $40 shopping spree to @SASJewelry from @couponclippin Ends 12/11 #giveaway #gifts #Christmas

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This giveaway will end on December 11, 2012 at 11:59 PM EST. The winner will be drawn via random.org. The winner will be notified via email and will have 48 hours to respond. Open to US residents only.

Disclaimer: I received the product mentioned above, no other compensation was received.? All views expressed are my own opinions.

Source: http://www.couponclippinmommy.com/2012/11/something-about-silver-family-tree.html

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Tuesday, November 27, 2012

Illuminating the no-man's land of waters' surface: Strong electric charge observed at the interface between oil and water is not due to impurities

ScienceDaily (Nov. 27, 2012) ? Water repelling molecules are said to be hydrophobic. The hydration -- or formation of water interfaces around hydrophobic molecules -- is important for many biological processes: protein folding, membrane formation, transport of proteins across an interface, the transmission of action potentials across membranes. It is involved as well in the process of creating mayonnaise, or in the fact that you can get rid of fat with soap. Hydrophobic interfaces although long studied, are poorly understood.

Here's an amusing kitchen-table experiment to illustrate waters unusual properties: put a drop of pure insulating oil in a glass of pure, non-conducting water, and create an electric field using two wires hooked up to a battery. You'll see the oil move from the negative to the positive pole of the little circuit you've created. You have created charge in a mixture that was neutral, and a huge amount of it too, judging from the speed at which the droplets move. The same thing happens for gas bubbles in water; the phenomenon of charging applies to all hydrophobic/water interfaces.

A century of debates

It's not a new discovery; scientists have observed the phenomenon in the middle of the 19th century. But despite more than a century of research, the reason why such a huge electric charge exists is still the subject of heated debate.

In an article published this week in Angewandte Chemie -- a journal of reference in the field -- EPFL scientist Sylvie Roke challenges a hypothesis put forward last spring in the same journal. With experimental proof to back her up, the holder of the Julia Jacobi chair in photomedicine makes her case: the phenomenon is not caused by the inevitable "impurities" present in oils, as her colleagues claim, but rather by certain intrinsic properties of the water molecules involved.

Show the unseeable

For proof, Roke turns to the technologies in which she is an expert -- nonlinear optics and light diffusion. Using carefully filtered lasers channeled through a complex circuit of mirrors and lenses, she "hits" her sample -- barely a drop -- and measures the wavelength of the light that escapes from it. With this she can detect whether or not there are nanoscopic molecules on the interface between the oil and the water.

The precision of the observations "shows that negative charges exist even in a total absence of surface impurities, and thus the explanation put forward by my colleagues, which was derived from charge measurements and chemical titrations of the bulk liquids, doesn't hold up," says Roke. "We have developed a unique apparatus that can distinctly measure the interfacial structure of a layer on the sub-nanometer length scale that surrounds a droplet of oil in water. Thus, we can 'see' what is on the interface, and do not have to deduce it from comparing bulk properties, which is far less accurate."

Disproving a hypothesis isn't enough to explain a phenomenon, however. Roke is studying a promising avenue, that explores the intrinsic quantum nature of the water molecule itself, which might be responsible for the phenomenon. "The measurements we've made as part of this refutation could be used to try and prove this explanation," she says. "It's fascinating, because quantum effects (the smallest of the smallest) might be responsible for macroscopic charging effects that influence so many properties that relate to the functioning of the human body."

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Story Source:

The above story is reprinted from materials provided by Ecole Polytechnique F?d?rale de Lausanne, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Kailash C. Jena, R?diger Scheu, Sylvie Roke. Surface Impurities Are Not Responsible For the Charge on the Oil/Water Interface: A Comment. Angewandte Chemie International Edition, 2012; DOI: 10.1002/anie.201204662

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/matter_energy/biochemistry/~3/4sUdXJpBTXU/121127130250.htm

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Nepali artists turn Everest garbage 'into gold'

Laurence Tan / Reuters, file

A basket of garbage sits at Everest Base Camp, with the Himalayan range seen in the background, in May 2011.

By Reuters

KATHMANDU, Nepal -- Fifteen Nepali artists were closeted for a month with a heap of 1.5 tons of trash picked up from Mount Everest. When they emerged, they had transformed the litter into art.

The 75 sculptures, including one of a yak and another of wind chimes, were made from empty oxygen bottles, gas canisters, food cans, torn tents, ropes, crampons, boots, plates, twisted aluminium ladders and torn plastic bags dumped by climbers over decades on the slopes of the world's highest mountain.

Kripa Rana Shahi, director of art group Da Mind Tree, said the sculpting -- and a resulting recent exhibition in the Nepali capital of Kathmandu -- was aimed at spreading awareness about keeping Mount Everest clean.

"Everest is our crown jewel in the world," Shahi said. "We should not take it for granted. The amount of trash there is damaging our pride."

Nearly 4,000 people have climbed the 29,035-foot Mount Everest, many of them several times, since it was first scaled by New Zealander Sir Edmund Hillary and Tenzing Norgay Sherpa in 1953.

Although climbers need to deposit $4,000 with the government, which is refunded only after they provide proof of having brought the garbage generated by them from the mountain, activists say effective monitoring is difficult.

PhotoBlog: Nepali teen says she is youngest woman to climb Mount Everest

Climbers returning from the mountain say its slopes are littered with trash, which is buried under the snow during the winter and comes out in the summer when the snow melts.

'Nothing goes to waste in art'
The trash used in the art works was picked up from the mountain by Sherpa climbers in 2011 and earlier this year and carried down by porters and trains of long-haired yaks.

The yaks were commemorated in one work. For another, empty oxygen cylinders were mounted on a metal frame to make Buddhist prayer wheels.

Another, by wall painter Krishna Bahadur Thing, is a Tibetan mandala painting showing the location of Mount Everest in the universe -- made by sticking yellow, blue and white pieces of discarded beer, food cans and other metals on a round board.

Climbers hoping to conquer the world's tallest peak hit a bottleneck over the weekend when the weather cleared, which caused a greater number of climbers to attempt the same route without the ability to pass one another. NBC's Stephanie Gosk reports.

Visitors said they were amazed at the way waste products were turned into useful items.

"It shows that anything can be utilised in an artistic way and nothing goes to waste in art," said 18-year-old fine arts student Siddhartha Pudasaini.

Complete World coverage on NBCNews.com

The art is on sale for prices from $15 to $2,300, with part of the proceeds going to the artists and the rest to the Everest Summiteers' Association, which sponsored the collection of garbage from the mountain, organizers said.

"Garbage on Everest is shameful. We are trying to turn it into gold here," association chief Wangchu Sherpa told Reuters.

More world stories from NBC News:

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Copyright 2012 Thomson Reuters. Click for restrictions.

Source: http://worldnews.nbcnews.com/_news/2012/11/26/15446567-turning-garbage-into-gold-nepali-artists-transform-everest-litter-into-art?lite

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Holyoke Mayor Ran As Gaming Opponent, Now Supports Casino Bid

HOLYOKE, Mass. (AP) ? A western Massachusetts mayor whose opposition to casino plans helped him win last year?s election at age 22 is now supporting a bid to bring a gambling resort to town.

Holyoke Mayor Alex Morse is expected to announce Monday that he is backing plans for a casino near Interstate 91 on the side of Mount Tom.

Morse says he changed his mind because a casino would be a big boost to the city?s struggling economy. He acknowledges flip-flopping on the issue and is prepared for a backlash, but he says it?s in the best interests of the city.

A 1-year-old law allows up to three resort-style casinos in Massachusetts, but just one in the western part of the state. Three major casino operators have proposed gambling resorts in Springfield.

Copyright 2012 The Associated Press.

Source: http://boston.cbslocal.com/2012/11/25/holyoke-mayor-ran-as-gaming-opponent-now-supports-casino-bid/

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Monday, November 26, 2012

Good Habits for iPhone Encourages You to Keep Doing the Things You've Always Wanted to Do

Good Habits for iPhone Encourages You to Keep Doing the Things You've Always Wanted to Do iOS: Good Habits helps you keep track of multiple activities and habits that you want to build over time. The app shows you a calendar of your current and longest unbroken chain lengths, shows you your to-dos as a checklist, and helps you stay motivated to keep your habit chains unbroken.

We've discussed how helpful Seinfeld's productivity secret (aka "Don't break the chain") can be, but to give it a try you'll need a good calendar or tool to tack your habit chain. Good Habits is a free utility that fits the bill nicely, and includes some additional features that offer visual cues to keep you motivated so you don't break the chain. Overdue items are marked in red, and if you're sick, traveling, or can't hit your to-do for some reason, you can always pause it so you can return to it without having to start a new chain. The app is open source, and available now in the iTunes App Store.

Good Habits (Free) | iTunes App Store

Source: http://feeds.gawker.com/~r/lifehacker/full/~3/2ke6mjb1VeY/good-habits-for-iphone-encourages-you-to-keep-doing-the-things-youve-always-wanted-to-do

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The new Patriots-Colts?

Green Bay looking for a little revenge Sunday night after last year's playoff loss

By Greg Bedard

NBCSports.com contributor

updated 6:23 p.m. ET Nov. 24, 2012

Greg Bedard

Sunday Night Football is turning into rivalry football.

A week after the Ravens and Steelers battled each other in the AFC North, one of the burgeoning NFC rivalries, Giants-Packers, will have another installment at MetLife Stadium.

With two young, elite quarterbacks in Aaron Rodgers and Eli Manning leading each team, Giants-Packers is looking a lot like the successor to Colts-Patriots, Tom Brady vs. Peyton Manning: two teams in different divisions who find a way to see each other often between the regular and postseason (sixth meeting since 2007 with Packers holding 3-2 edge).

Both Giants' wins against the Packers have come in January (2007 and ?11), in the postseason, as the Giants marched into Lambeau Field, left with a physical victory and went on to win the Super Bowl.

Last year?s 37-20 loss to the Giants ended a dream season for the Packers, who were 15-1 at the time. They lost because their execution was terrible ? giving up a Hail Mary touchdown, dropping four passes, turning the ball over four times and a plethora of missed tackles.

It?s safe to say the Packers (7-3) haven?t forgotten their performance, and the beating the Giants (6-4) put on them. Not that Green Bay will acknowledge that. It is focused on this game, not the past.

?Watching the playoff game, it wasn?t fun, I think that?s obvious,? coach Mike McCarthy said this week. ?But it?s part of our preparation for the week. A lot of the same players played in that game, played in the regular-season game (in 2011). We all understand how the season ended, but we?re focused on 8-3.?

A look at the keys for each team:

Packers
Rodgers can?t hold the ball:
Packers quarterback Aaron Rodgers is an exceptional player with smarts, a terrific arm and very quick feet that allow him to keep plays alive or make them on his own. But sometimes Rodgers tries to do too much, tries to keep the play alive too long and that can lead to protection issues. Rodgers has been sacked 32 times this season, which is more than any other NFL quarterback. Some of those are on Rodgers for holding onto the ball too long. While the Giants rank just 13th with 25 sacks, they are capable of dominating a game with ends Jason Pierre-Paul, Osi Umenyiora and Justin Tuck. McCarthy needs to put in a quick-pass game plan, and Rodgers needs to stick to it outside of called shot plays.

Stop the run: The Giants have gotten a bit out of whack lately with their pass-run balance, but they?ll look to establish the run more against the Packers. The Giants need the run to make their passing game, which has struggled of late, really click. The Packers (11th in the league) have done a nice job against the run now that their personnel have settled down. The defensive line of Ryan Pickett, Jerel Worthy and B.J. Raji are very sturdy and have allowed inside linebackers A.J. Hawk and Brad Jones to fill nicely. The Packers want the Giants to stay pass heavy because they?re in a slump and could get some three-and-outs that could get the Packers going.

Do your job: When the Packers have struggled the past few years, it hasn?t been because of what the opponent has done, it?s because the Packers have killed themselves with poor execution. If the Packers execute their blocks, catch the ball and tackle well, they?re a tough matchup for anyone. But they haven?t done that consistently. This also includes kicker Mason Crosby, who has been in a terrible slump. He has to make his kicks early because if he?s an issue, it could change the way the Packers play in Giants' territory for the rest of the game.

Giants
Protect up front:
Packers defensive coordinator Dom Capers will probably look to bring pressure against the Giants because his front seven has a tough time winning with standout outside linebacker Clay Matthews out. Capers also knows he can?t let Eli Manning have clean reads, and his line is ripe for the taking. The Giants have had a rough time of late protecting Manning ? they were destroyed by the Bengals. Expect the Packers to throw a ton of overload blitzes at the right side of the Giants? line, where guard Kevin Boothe and David Diehl have been the weak spots. The Giants chip a lot with the running backs out of the backfield, and they might have to think about keeping a tight end in to help with protection. The Packers will be coming.

Get after Rodgers: With excellent right tackle Bryan Bulaga out for the season, the Packers have had to do a line dance with left guard T.J. Lang moving to right tackle, and backup Evan Dietrich-Smith in at left guard. Both compete really hard but are limited in their ability at those spots. Left tackle Marshall Newhouse has had problems on occasion this season, and center Jeff Saturday is not the player he once was. The Giants? defensive line should be able to dominate this game up front against the run and the pass. And that should give the Giants a really good chance of winning the game.

Get physical with the Packers? receivers: The Packers have talented targets for Rodgers in Greg Jennings (questionable after abdominal surgery), Jordy Nelson, James Jones, Randall Cobb and tight end Jermichael Finley. But the book on them is that they don?t like contact and can be thrown off their game if defensive backs are physical with them. It also throws off the timing of the passing offense and causes Rodgers to hold the ball longer. The Giants should try to be physical with the Packers? receivers, but they should be careful with Cobb. The speedy slot receiver is lining up in different spots every week, including running back. He could be a big problem if the Giants don?t get their hands on him. That means everyone ? ends, outside linebackers and defensive backs ? needs to make sure they hit Cobb on his releases. If he runs free, he might go all the way to the end zone.

? 2012 NBC Sports.com? Reprints

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The new Patriots-Colts?

Bedard: With two young, elite quarterbacks in Aaron Rodgers and Eli Manning leading each team, Giants-Packers is looking a lot like the successor to Colts-Patriots, Tom Brady vs. Peyton Manning.

Source: http://nbcsports.msnbc.com/id/49949043/ns/sports-nfl/

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Sunday, November 25, 2012

DIY Pain Relieving Cream Helps Relax Sore Muscles and Joints

DIY Pain Relieving Cream Helps Relax Sore Muscles and JointsMaking a cream or massage oil using camphor, menthol, and eucalyptus works great to help relax coughing when applied to your chest and throat, relax sore muscles, and may also diminish joint pain.

Household weblog One Good Thing by Jillee found that nearly all therapeutic topical creams and ointments contain either camphor, menthol, or eucalyptus. Jillee's son was recently diagnosed with a skeletal disorder that causes a lot of back pain and she wanted to reduce the amount of over-the-counter analgesics he had to take everyday. Through trial and error she came up with the recipe for her cream with helps her son and makes a great therapeutic massage oil or cream.

To make it you melt coconut oil and beeswax pellets together under gentle heat. After removing from the heat source add camphor crystals or oil, menthol crystals or oil, and eucalyptus oil. Mix thoroughly and pour the oil into a container. It will solidify when completely cooled but was liquify again when applied to the skin, just like coconut oil itself. Jillee also notes that if you don't want to bother with making your own cream you can purchase a jar of vitamin E cream and add the three essential oils.

The menthol and camphor should also help relieve suffering from a chest cold by applying to your chest in a way similar to Vick's Vaporub and also help with muscle pain.

Make Your Own Homemade Pain Relieving Cream | One Good Thing by Jillee

Source: http://feeds.gawker.com/~r/lifehacker/full/~3/iZLnAChTK4M/diy-pain-relieving-cream-may-helps-relax-sore-muscles-and-joints

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GLHFCasting ? Real Estate agents

If you have made the choice to buy or sell a home, finding a reputable real estate agent can make this process uncomplicated, less stressful, and more economical. Professional realtors are experienced with predict the housing market and the buying/selling process to help their customers get the best deal at the best time. But there are many agents who may not be right for you and choosing the right one can be difficult. During the selection process, make sure you find out what credentials they have and what tools they can utilize. Pay close attention to the way they talk and listen to you, the upkeep of their office, and how they prefer to be paid. By taking some time, you can find the right realtor that will keep you at the top of the real estate game. Herriman Homes for sale

Source: http://www.glhfcasting.com/real-estate-agents/

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Saturday, November 24, 2012

CHINA MONEY-China creates taxation income a financial process tool

Thu Nov 22, 2012 1:01am EST

* Sharp enlargement of mercantile deposits over past decade

* Such deposits can be used by regulators to inject money

* Cash injections in late 2012 to strech record level

* PBOC might not need to cut RRR for rest of year

By Lu Jianxin and Pete Sweeney

SHANGHAI, Nov 22 (Reuters) ? Government revenues deposited
in Chinese blurb banks have grown so vast that regulators
have been means to use them as a financial process tool, increasing
the pointing with that Beijing can conduct growth.

By sensibly auctioning supervision deposits and by
directly redistributing income lifted from taxes and fees to
companies and supervision departments, a Ministry of Finance
(MOF) is now means to use supervision assets to influence
short-term appropriation costs in a wider economy.

This means that marketplace players who guard a central
bank?s open marketplace operations for clues as to a instruction of
monetary process contingency keep another eye on a cycle of funds
moving in and out of accounts tranquil by a MOF.

?Fiscal deposits have spin a vital cause to change the
central bank?s financial process as good as income markets,? pronounced a
senior merchant during a Chinese state-owned bank in Beijing.

?In months when a marketplace is brief of liquidity, the
ministry can also use supervision deposition auctions to assistance the
central bank boost income supply. In this sense, mercantile deposits
are indeed being used as a financial apparatus as well.?

THE WAY IT WORKS

Chinese companies and other institutions, that compensate taxes
and fees to a MOF and a internal offices, contingency deposition these
payments into accounts during designated blurb banks in the
form of mercantile deposits. Such deposits can?t be used by
commercial banks and play no purpose in financial policy.

However, 3 times per month, a blurb banks hand
over all of these deposits to a People?s Bank of China (PBOC),
where they spin partial of a PBOC?s financial base. This base
money can be possibly defended in times of additional liquidity, or
pushed behind into a complement in a form of MOF spending, deposit
auctions and refunds on taxation overpayments.

A diminution in mercantile deposits on blurb banks? balance
sheets therefore implies some-more income has been handed over to the
state and is now accessible for income injection.

On months when mercantile deposits drop, a PBOC customarily has
less need to inject short-term income into a complement in a form
of retreat repurchase agreements, given income is entering the
system by channels tranquil by a MOF.

There are transparent anniversary characteristics to a upsurge of
funds.

In December, for example, a MOF typically injects large
amounts of income in a form of taxation refunds, subsidies to
government institutions and income transfers to companies in
pillar industries.

Deposits also tend to diminution in March, June, September,
and November, while other months customarily uncover net fiscal
deposits increasing, tightening income supply in a banking
system.

RECORD INJECTION

An bargain of a MOF?s position on any given month
can be simply subsequent from monthly information on blurb banks?
end-month mercantile deposits published by a PBOC.

The method accessible a mercantile over-abundance of 829.6 billion yuan
($133.2 billion) in a initial 10 months of 2012, and is set to
generate some-more over-abundance in a final dual months.

A Reuters research of a information shows that a MOF is likely
to siphon a record high 1.6 trillion yuan into a complement in the
last dual months of this year. Data suggests it injected slightly
lesser amounts during a same duration given 2008, compared to
under 580 billion yuan in 2007 and reduction than 220 billion yuan in
2002 during a same period.

The supervision has designed to record an altogether budgetary
deficit of 800 billion yuan for 2012, implying that a entirety
of a mercantile over-abundance will be plowed behind into a economy,
supplemented by additional necessity spending.

THE AUCTION MECHANISM

The impact of supervision spending on subsidies, refunds and
transfers is formidable to magnitude precisely, though a auction of
deposits combined by supervision revenues is easier to manage.

Such deposits are auctioned for specific durations of time -
usually between 3 and 6 months ? definition regulators and
money marketplace participants can design how prolonged a income will
be in a system.

This year?s auction volume for such deposits is equivalent
to around half of a sum volume of open marketplace operations
conducted by a executive bank, injecting a record 690 billion
yuan into blurb banks so distant this year, adult from 450 billion
yuan in 2011 and 170 billion yuan in 2008.

This means that even as a PBOC has mutated its
open-market operations to concentration roughly exclusively on a usage
of retreat repos with tenors of reduction than one month to manage
the interbank income supply, it has a massive
pool of accessible deposits to tumble behind on if necessary.

The coherence this toolset provides China?s economic
managers has authorised them to conflict calls to revoke a reserve
requirement ratio (RRR) during blurb banks for a third time
this year, even as world?s second-largest economy slowed to its
slowest in 3 years in a third quarter.

This in spin authorised regulators to continue to fight
inflation ? that regulators fear would be aggravated by another
RRR cut given such cuts inject income into a complement that
cannot simply be pulled behind out ? but formulating a liquidity
crisis.

As a result, traders pronounced that short-term income rates for
the benchmark seven-day bond repurchase rate have
remained in gentle domain around or subsequent 3 percent even
as a executive bank has authorised income to empty from a system
through open marketplace operations for a final 3 weeks.

Traders design rates to sojourn fast or even diminution in
most partial of December.

Although 2013?s bill will not be motionless until subsequent March,
if China?s economy continues to recover, mercantile revenues will
likely arise further, giving a Ministry of Finance even more
firepower to change rates.
($1 = 6.2302 Chinese yuan)

(Editing by Kim Coghill)

Article source: http://www.reuters.com/article/2012/11/22/markets-china-debt-idUSL4N0920TO20121122

Source: http://thecashcollector.com/china-money-china-makes-tax-revenue-a-monetary-policy-tool/?utm_source=rss&utm_medium=rss&utm_campaign=china-money-china-makes-tax-revenue-a-monetary-policy-tool

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Israeli forces kill Gaza man despite cease-fire

By Ayman Mohyeldin and Andy Eckardt, NBC News

Updated at 7:55 a.m. ET: GAZA -- A 20-year-old Palestinian was killed and 10 others injured by Israeli forces Friday, Palestinian medical officials told NBC News, despite the U.S.-brokered cease-fire declared Wednesday.

The men were shot on the Gaza side of the border as they tried to access their farmland in the eastern part of Khan Younis, the Palestinian Medical Service said early Friday.

Palestinian Foreign Minister Riad Malki said the shooting had broken the cease-fire, Reuters reported.?Malki, speaking at a meeting with Italian Foreign Minister Giulio Terzi, called the incident ?a clear violation of the agreement and should not be repeated.?

Bernat Armangue / AP

Israel's military said it had accomplished its objectives while Hamas claimed victory after the two sides exchanged deadly airstrikes and rocket attacks for over a week.

The Israeli Defense Forces imposes a no-go zone on the Gaza side of the border, but the officials said the men believed they would be able to access their farmland safely during the truce, which began late Wednesday.

A spokesman for the IDF told NBC News that it did not have any immediately information about the death of Palestinian.

Israel arrests suspects in Tel Aviv bus bombing

The spokesman said there were several "incidents of disquiet and unrest at the Gaza border" and that "Israeli soldiers fired warning shots in the air.?

When the rioters did not comply, the soldiers responded by firing at the rioters legs, the spokesman added.

The cease-fire between Israel and Hamas had been holding firm, with scenes of joy among the ruins in Gaza on Thursday, including a celebratory rally past wrecked houses and government buildings.

However, schools stayed closed in southern Israel, where nerves were jangled by warning sirens - a false alarm, the IDF said.

Residents of Gaza return to their homes with hope the cease-fire persists. ITV's John Ray reports.

The truce was the fruit of intensive diplomacy by Egypt?s new Islamist regime, spurred by U.S. President Barack Obama, who sent Secretary of State Hillary Clinton to the Middle East.

Reuters contributed to this report.

More world stories from NBC News:

Follow World News from NBCNews.com on Twitter and Facebook

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Source: http://worldnews.nbcnews.com/_news/2012/11/23/15382148-israeli-forces-kill-gaza-man-despite-cease-fire?lite

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WordPress Course ? WordPress Crash Course | Computers ...

You are here: Home / General / WordPress Course ? WordPress Crash Course



WordPress Course - WordPress Crash CourseYou get two solid hours of online video instruction where you watch my computer screen as I build a fully functional, search engine optimized site .

In this WordPress tutorial series you?ll be able to watch me every step of the way and pause the video to perform the same action for yourself.

Currently there are 37 videos in the member?s area and I may add a few more based upon member feedback. I purposely kept each video short, most are around five minutes. This is so you?ll have an easy reference should you need to go back and review a specific task. You can watch a short sample of one of the training videos below.

I?ve also added a 23 step, quick reference check list for you to refer to after watching the videos. You can print out the list and check off steps as you complete them. This will help you set up your blogs and websites very quickly without missing important steps.

The WordPress tutorial videos are made with a high quality screen capture software and they are in an extra large format so you can clearly see everything I?m doing. You can forget about blurry, hard to understand YouTube videos. I?m also speaking in clear English with no hard to understand accents (well, I guess I do have an American accent).

Other WordPress training courses teach you how to get your blog up and running over a period of weeks. The WordPress Crash Course is presented in a way that will help you get your blog online with all the essential elements and looking great TODAY, even if you are a complete beginner.

I cut out all of the fluff and unnecessary information that you would normally find in other courses?


Read more?

Posted by Dan on Friday, November 23, 2012 at 10:13 am?
Filed under General ? Tagged with

Source: http://www.theyellowads.com/computers_technology/wordpress-course-wordpress-crash-course/

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Friday, November 23, 2012

3 Important Online Marketing Trends for 2013

Although it?s much easier to leave things for the last minute, it?s best to prepare ahead of time, especially when it comes to your website. It?s hard to stay on top of every single change that happens with search engines and social media, but doing a quick end-of-year assessment of your website or social media strategy can help you to align your online presence more strategically and effectively with your overall marketing goals.

Here are some things that you will want to focus on for 2013:

Google+

Google+ profiles and creating posts on your profile can boost your ranking by allowing you to stand out in search results for the posts you have authored. Like a blog, it keeps your name attached to fresh content, connecting you to the content on your site. In the upcoming year, content, authorship (see why it?s important), and social interactions are going to play an even bigger role in your ranking and search engine optimization, so make sure your site is engaging with all the avenues that give it a boost.

Mobilization

Mobile devices now account for more than 10% of web traffic, an increase of 35% from last year (see: Source). Consumers like their mobile devices for its on-the-go?convenience, researching products, finding sales, comparing prices, and making purchases. If you haven?t already optimized your site, it should probably be at the top of your list for 2013.

The use of mobile wallets is on the rise and will be increasingly available across different devices, so as more consumers begin to pay for their purchases using their phones, businesses need to be prepared and take advantage of this trend. Investigate whether or not your business needs a mobile payment system on your site to make it easier for consumers to buy your products.

Social Everything

I never get tired of saying how important social media is. It has become an important and effective way of reaching an audience, and makes it much easier for people to find you or your business. 80% of active internet users visit social networks and blogs with 22% of their overall time spent on social media sites such as Facebook, Twitter, and Pinterest (see: Source). You may already have accounts but if you haven?t used them to your full advantage, take the time to investigate the ways you can keep content fresh and new by checking out what other people are doing and how they?re making it work.

Tip: It is very easy to have content become dated on social media sites. Set a schedule for when to post content and what it will be about. Put it in your calendar or set it as a reminder. That will help you to get the results you want.

Source: http://www.netconnexion.com/blog/3-important-online-marketing-trends/

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Nintendo Wii U (finally) gets YouTube app, works on GamePad too

Nintendo Wii U finally gets YouTube app, works on Gamepad too

If you managed to grab a Wii U ahead of today's festivities, you'll now be able to fall into carb-heavy slumber while watching your favorite YouTube hits. Users can browse through the GamePad but also beam the video content through to their big screen, all in a navigation setup resembling its predecessor's YouTube client, although shortcuts are now more visible along the left edge. Download the app for free, direct from your Wii U menu, starting today.

Continue reading Nintendo Wii U (finally) gets YouTube app, works on GamePad too

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Source: http://www.engadget.com/2012/11/22/nintendo-wii-u-finally-gets-youtube-app-works-on-gamepad-too/

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Gratitude Healthy: 10 Reasons Why Being Thankful Is Good For You

Thanksgiving offers the opportunity to do something we should really be doing every day of the year: Thinking about, and expressing, what we're grateful for.

And really, there's a whole host of reasons why we should make gratitude a daily practice -- research has shown that being thankful confers a whole host of health benefits, from improved immune systems, to feelings of connectedness, even higher team morale.

We gathered some of the biggest health benefits -- both physical and mental -- of gratitude. Tell us in the comments: What are you most grateful for this year?

  • Good For Teens' Mental Health

    <a href="http://www.huffingtonpost.com/2012/08/11/gratitude-teens-happier_n_1749118.html">Grateful teens are happier</a>, according to a study presented at the annual meeting of the American Psychological Association this year. Researchers also found that teens who are grateful -- in the study, defined as having a <a href="http://www.huffingtonpost.com/2012/08/11/gratitude-teens-happier_n_1749118.html">positive outlook on life</a> -- are more well-behaved at school and more hopeful than their less-grateful peers. "More gratitude may be precisely what our society needs to raise a generation that is ready to make a difference in the world," study researcher Giacomo Bono, Ph.D., a psychology professor at California State University, said in a statement.

  • Boosts Well-Being

    Being constantly mindful of all the things you have to be thankful for can boost your well-being, research suggests. In a series of experiments detailed in a 2003 study in <a href="http://greatergood.berkeley.edu/pdfs/GratitudePDFs/6Emmons-BlessingsBurdens.pdf">the <em>Journal of Personality and Social Psychology</em></a>, daily exercise practices and listing off all the things you are thankful for are linked with a brighter outlook on life and a greater sense of positivity. "There do appear to exist benefits to regularly <a href="http://greatergood.berkeley.edu/pdfs/GratitudePDFs/6Emmons-BlessingsBurdens.pdf">focusing on one's blessings</a>," the researchers wrote in the study. "The advantages are most pronounced when compared with a focus on hassles or complaints, yet are still apparent in comparison with simply reflecting the major events in one?s life, on ways in which one believes one is better off than comparison with others, or with a control group."

  • Linked With Better Grades

    Grateful high-schoolers have <a href="http://people.hofstra.edu/jeffrey_j_froh/spring%202010%20web/10.1007_s10902-010-9195-9[1].pdf">higher GPAs</a> -- as well as better social integration and satisfaction with life -- than their not-grateful counterparts, according to a 2010 study in the <em>Journal of Happiness Studies</em>. Researchers also found that grateful teens were less depressed or envious. "When combined with previous research, a clearer picture is beginning to emerge about the <a href="http://people.hofstra.edu/jeffrey_j_froh/spring%202010%20web/10.1007_s10902-010-9195-9[1].pdf">benefits of gratitude</a> in adolescents, and thus an important gap in the literature on gratitude and well-being is beginning to be filled," researchers wrote.

  • Makes You A Better Friend To Others

    According to a 2003 study in the <a href="http://greatergood.berkeley.edu/pdfs/GratitudePDFs/6Emmons-BlessingsBurdens.pdf">the <em>Journal of Personality and Social Psychology</em></a>, gratitude could also boost pro-social behaviors, such as helping other people who have problems or lending emotional support to another person.

  • Helps You Sleep Better

    Writing down what you're thankful for as you drift off to sleep can help you get better ZZs, according to a study in the <a href="http://onlinelibrary.wiley.com/doi/10.1111/j.1758-0854.2011.01049.x/abstract">journal <em>Applied Psychology: Health and Well-Being</em></a>. Specifically, researchers found that when people spent 15 minutes jotting down what they're grateful for in a journal before bedtime, they <a href="http://www.psychologytoday.com/blog/minding-the-body/201111/how-gratitude-helps-you-sleep-night">fell asleep faster</a> and stayed asleep longer, <em>Psychology Today</em> reported.

  • Strengthens Your Relationship

    Being thankful for the little things your partner does could make your relationship stronger, according to a study in the journal <em>Personal Relationships</em>. <em>The Telegraph</em> reported on the study, which showed that journaling about the <a href="http://www.telegraph.co.uk/women/sex/7756775/Gratitude-for-little-things-is-key-to-relationships.html">thoughtful things your partner did</a> was linked with a beneficial outcome on the relationship.

  • Benefits The Heart

    A 1995 study in the <em>American Journal of Cardiology</em> showed that <a href="http://www.ncbi.nlm.nih.gov/pubmed/7484873">appreciation and positive emotions</a> are linked with changes in heart rate variability. <blockquote>[This] may be beneficial in the treatment of hypertension and in reducing the likelihood of sudden death in patients with congestive heart failure and coronary artery disease.</blockquote>

  • Is Good For Team Morale

    Athletes are <a href="http://www.eric.ed.gov/ERICWebPortal/search/detailmini.jsp?_nfpb=true&_&ERICExtSearch_SearchValue_0=EJ811262&ERICExtSearch_SearchType_0=no&accno=EJ811262">less likely to burn out</a> and more likely to experience high life satisfaction and team satisfaction when they are grateful, according to a 2008 study in the journal <em>Social Indicators Research</em> of high-schoolers.

  • Linked WIth Better Immune Health

    Gratefulness is linked with optimism, which in turn is linked with <a href="http://women.webmd.com/features/gratitute-health-boost">better immune health</a>, WebMD reported. For example, a University of Utah study showed that stressed-out law students who were optimistic had more immune-boosting blood cells than people who were pessimistic, according to WebMD.

  • Protects You From Negative Emotions That Come With Extreme Loss

    WebMD reported that negative events can boost gratitude, and that gratitude can help to <a href="http://women.webmd.com/features/gratitute-health-boost">boost feelings of belonging</a> and decrease feelings of stress. For example, a survey showed that feelings of gratitude were at high levels after 9/11, according to WebMD.

  • What It Means to Practice Gratitude

    Question: What does it mean to practice 'gratitude' and why should I do it?

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Source: http://www.huffingtonpost.com/2012/11/22/gratitude-healthy-benefits_n_2147182.html

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Thursday, November 22, 2012

Worst Gift I've Ever Gotten: Spouses Spill All

It's the thought that counts, right? Wrong! Unless any of these items were specifically requested by your long-time spouse, don't even think about buying your partner a self-help book, a vacuum cleaner or anything having to do with exercise this holiday season.

Or so says a whole host of post 50 husbands and wives we spoke with about the worst gifts they'd ever gotten from their spouses for Christmas.

Some said they couldn't believe their partners of many years had stooped to the level of buying them a gift card or, even worse, white granny panties. How un-sexy does he think I am? Others said they'd never forgive their spouse for buying them an ugly Christmas sweater -- and nothing more. What were they thinking?

"In my 14 years of marriage, I'd say the worst present I ever received was a state-of-the-art barbeque grill because it was clearly for him to put out by the pool ... and not for me! Ha!," said Meg Beattie Patrick.

"The best present I ever received from a husband was a pair of Riedell Figure Skates with Sheffield blades ... I cried more than when I received diamonds or pearls. A gift is about what makes the essence of a person happy ... and ice skating is like flying!" she added.

Katya Wowk recalled that Christmas 2010 was a huge disappointment for her, present-wise.

"Earlier that year the very first iPad was released and my husband purchased one for himself the minute they were made available," she said. "For the next several months I watched with envy as he played with his beloved tech toy for hours on end, occasionally showing me some of the wonderful apps he downloaded. I ooh?d and ah?d and hoped that I would be the lucky recipient of an Apple iPad for Christmas.

"My heart sank when I saw the Tiffany PMS 1837 bag waiting for me to open it on Christmas morning. What a huge bummer that was," she added. "I wasn?t ungrateful and I certainly didn?t express my disappointment, but my husband could nonetheless tell that this was not the perfect gift."

Melissa Bigelow said her worst gift ever was a Roomba.

"Worst gift ever was a Roomba is the vacuum cleaner disk that circulates throughout the house and supposedly vacuums for you (given with the best of intentions as our fourth child was just born and he thought it would be helpful," she said. "The kids thought it was great, like a motorized pet. I was bummed to get a housecleaning tool as a gift, thereby solidifying my job as 'housewife'. Because I wanted something romantic, I asked him to return it, which he refused to do, and I wouldn't either so we drove around with it in the back of the car for months before finally giving it away."

Daniel Fried said he couldn't believe the year his wife bought him a book on "healing his emotional self."

"I was thinking, 'this is no present ... this is a sign you want me to change'," he said. "I'd rather get a tie than a self-help book.

"It's like buying your spouse an exercise mat or weights," he added. "You are sending a message that you want them to improve in some way."

Cathlyn Robinson said her "worst present story" has to do with how important Christmas morning stockings have always been to her and her very English family.

"One Christmas morning, we were all opening our stockings ... except me," she said. "My husband had forgotten to get my anything for my stocking and it was completely empty. He felt so badly that he ran out to 7-11 and bought me trashy magazines and bad candy.

"A very nice try but way too late! Otherwise, he does well on gifts ... and ever since that year, my stockings are full on Christmas morning," she said.

One woman said her worst Christmas was the year her husband's family was visiting and he asked everyone to buy her a different cooking pot or pan so that she'd have a complete set. One man said he hated receiving a giant exercise ball one year. "I didn't even know how to use the thing," he said.

So what was your worst Christmas present ever from a spouse? Let us know in comments. And, um, happy holidays!

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Source: http://www.huffingtonpost.com/2012/11/22/worst-gift-ive-ever-gotten_n_2159250.html

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Novel therapeutic advancement in search for heart muscle progenitor cells: New hope for heart attack patients

ScienceDaily (Nov. 22, 2012) ? Breakthrough in heart research: The research team from Professor Katja Schenke-Layland of the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB in Stuttgart has discovered cell surface markers that enable the identification and isolation of living functional cardiovascular progenitor cells (CPCs). For the first time, therapeutically relevant CPCs can be derived from induced-pluripotent stem cells (iPS) cells. CPCs, which are typically only found in fetal development, can become all of the different cell types of the heart and can integrate into heart muscle tissue after injection.

An estimated 17 million people die from cardiovascular disease each year. Although mortality rates are declining, heart attacks are still among the most frequent causes of death in the developed world. Often, the cause of a heart attack is the closure of a coronary artery that supplies blood to the heart, which kills heart muscle cells. Cardiomyocytes, which are the heart muscle cells responsible for the contraction of the heart, are not able to regenerate after a heart attack. The massive loss of cells and tissue, and the highly restricted regeneration capacity of the adult heart, lead to an impaired blood supply throughout the body that drastically affects a patient's quality of life. To restore the heart's function after a major heart attack, clinicians require functionally mature cardiomyocytes that perform like the native cells in the adult heart to replace the cells that were killed.

The production of such functional cardiomyocytes from well-defined cardiovascular progenitor cells (CPCs) is the focus of the research team led by Prof. Dr. Katja Schenke-Layland from the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB in Stuttgart and her colleagues, Dr. Ali Nsair of the University of California Los Angeles (UCLA) and Prof. Dr. Robb MacLellan of the University of Washington in Seattle, who have now succeeded in identifying such cells in a mouse model. The work could revolutionize the treatment of heart disease.

Development of heart muscle cells from precursor cells

Myocardial cells -- as well as endothelial cells and smooth muscle cells -- develop from CPCs during the embryonic development of humans and other animals. There has been a significant amount of research effort towards discovering a path for the clinical application of these cells in patients. The reason for the lack of success is that the markers that help to identify CPCs, such as Islet1 or Nkx2.5, are located in the nucleus of the cells. The use of these cell markers modifies the cells rendering them therapeutically unusable, making the identification of safe cell-surface markers essential.

Surface markers identified for cardiovascular progenitor cells

On this task, the research team of Professor Katja Schenke-Layland from the Fraunhofer IGB in Stuttgart, Prof. Dr. Robb MacLellan and Dr. Ali Nsair of the University of California Los Angeles (UCLA), where Schenke-Layland previously worked before returning to Germany to join the Fraunhofer-Gesellschaft's Attract Program, focused their research. With success: They were able to identify two markers, the receptors Flt1 (VEGFR1) and Flt4 (VEGFR3), on the surface of CPCs with which these cells can be clearly identified while fully preserving their biological function. This discovery allows scientists to isolate clinically relevant cardiovascular progenitor cells that can be functionally matured.

In the search for surface markers, the researchers investigated the cardiovascular progenitor cells using microarray gene expression profiling. These studies show exactly which genes are active at a specific point in time. The resulting data from this analysis were compared to the sequencing data from existing databases of already known as cell markers.

From induced-pluripotent stem cells, cardiovascular progenitor cells are developed

Encouraged by the success of being able to identify and isolate living CPCs, the researchers sought out to derive the cells from induced-pluripotent stem (iPS) cells. For this purpose, they used a method for which the Japanese scientist Shinya Yamanaka was recently awarded the 2012 Nobel Prize for Medicine. This work, published just six years ago, demonstrated that only four proteins are responsible for the embryonic state of cells (Takahashi K, Yamanaka S. Cell 2006, 126 (4): 663 -676). He brought those four genes into differentiated -- mature and specialized -- cells, which then returned them back to an embryonic state. From these cells, which he called iPS cells, scientists can develop all cells of the body, such as liver cells, nerve cells or heart muscle cells.

In their study, the researchers used cells from a mouse strain in which the cells are labeled with a visible green fluorescent protein (GFP) that can be identified with a fluorescence microscope. The cells from these mice were then reprogrammed with the same four genes discovered by Yamanka, resulting in iPS cells that could be easily identified.

In a next step, the researchers cultured the GFP-labeled iPS cells in the laboratory under different conditions with cell-influencing solutions such as growth factors. "Using our newly established cell surface markers, we could detect and isolate the Flt1 and Flt4 positive CPCs in culture," says Schenke-Layland. "When we cultured the isolated mouse CPCs then in vitro, they actually developed -- as well as the embryonic stem cell-derived progenitor cells -- into endothelial cells, smooth muscle cells and more interestingly into functional heart muscle cells."

iPS cell-derived CPCs integrate into the living mouse heart

But how do the developed CPCs behave in living organisms? Can these cells really integrate into tissue and regenerate heart muscle? To answer these questions, the scientists injected the GFP-labeled CPCs into the hearts of living mice. After 28 days, the researchers analyzed the hearts and saw that the green fluorescent cells had developed into beating heart muscle cells and had fully integrated into the myocardial tissue of the mouse.

Enormous potential for heart research

Researchers have long tried to stimulate the regeneration of heart muscle cells. For this purpose, they inject stem cells or stem cell-derived cardiomyocytes into the heart. Although the majority of studies found a slight improvement in heart function, in most cases, neither long-term integration nor the differentiation of the cells into heart muscle has been demonstrated.

The result of the group from Schenke-Layland, Nsair and MacLellan provides the first opportunity to generate functioning heart muscle cells, which integrate into the heart muscle. "We are currently focusing on research with human iPS cells. If we can show that cardiovascular progenitor cells can be derived from human iPS cells that have the ability to mature into functional heart muscle, we will have discovered a truly therapeudic solution for heart attack patients," hopes the scientist.

The work of the research group has been funded by the German-American funding from the Federal Ministry of Education and Research (BMBF) and the California Institute for Regenerative Medicine (CIRM), as well as the Fraunhofer-Gesellschaft (Attract Program), the Ministry of Science, Research and the Arts of Baden-W?rttemberg, and the US National Institutes of Health (NIH).

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Story Source:

The above story is reprinted from materials provided by Fraunhofer-Gesellschaft.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Ali Nsair, Katja Schenke-Layland, Ben Van Handel, Denis Evseenko, Michael Kahn, Peng Zhao, Joseph Mendelis, Sanaz Heydarkhan, Obina Awaji, Miriam Vottler, Susanne Geist, Jennifer Chyu, Nuria Gago-Lopez, Gay M. Crooks, Kathrin Plath, Josh Goldhaber, Hanna K. A. Mikkola, W. Robb MacLellan. Characterization and Therapeutic Potential of Induced Pluripotent Stem Cell-Derived Cardiovascular Progenitor Cells. PLoS ONE, 2012; 7 (10): e45603 DOI: 10.1371/journal.pone.0045603

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/heart_disease/~3/BY4-eiieI8A/121122112833.htm

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